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News and updates from the PTR-MS community

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Posts Tagged ‘ion chemistry’

PTR-MS now with Patented Ion-Chemistry Quality and TRU-E/N

The proprietary TRU-E/N™ method for utmost quantification accuracy

Founded by the inventors of Proton-Transfer-Reaction – Mass Spectrometry more than 20 years ago, IONICON has always been renowned for absolutely precise control of the ion chemistry during chemical ionization.

ION-BOOSTER funnel and hexapole ION-GUIDE with TRU-E/N

For IONICON this fact is still true even after the introduction of Radio Frequency (RF) components for focusing and transferring the ions from the reaction region into the mass analyzer.

Several manufacturers of CIMS instruments are trying to boost the sensitivities to the high spheres in which IONICON’s PTR-MS instruments perform. However, this comes at an extremely high cost: control over the ion-chemistry is lost. Undefined fragmentation of analytes renders a comparison of results with values published in the ample PTR-MS literature and, most importantly, accurate quantification impossible. As the reduced electric field strength (E/N) in the reaction region cannot be calculated any more as soon as RF devices are implemented, no E/N values can be stated upon publishing of measurements*, which seriously limits the reproducibility of results. (more…)

PTR-MS is not PTR-MS?!

IONICON-grade PTR-MS Quality: Important Ion Chemistry Dimensions

You’ve got used to expecting an IONICON-grade instrument when you see the abbreviation “PTR-MS“? After all, more than 350 IONICON PTR-MS instruments yielded hundreds of high-impact papers and allowed gaining insights in various science domains. But, what determines a real IONICON PTR-MS and how does it compare to other CIMS technologies that sometimes are also claimed to be “PTR-MS”?

Watch our webinar and learn more about the 4 quality dimensions that determine genuine PTR-MS, a technology only available from IONICON:

Don’t have time for the full webinar? Read about the 4 quality dimensions on our website.